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Table 2 shows the median effective dosages of each antidepressant in children ages 2 to 15, stratified into different subgroups based on age and birth order. Children with depressive symptoms were more likely to receive higher doses of some therapies than were children with other symptoms, such as anxiety, or who were depressed by stress or social loss.

Table 2. Median Effective Dosages Of Common Antidepressants For Children Ages 2 To 15

No. of Cases Median Patients 2–3 1–2 1 3–4 2 4–6 6+ 16.6 15.4 15.1 14 25 22.9 22 16–17 1 13 5 0 21 12 2–3 10 4 0 13 5 3–4 14 8 0 19 10 4–6 13 7 0 6

Although the data for most of drugs are pediatric populations, our results also demonstrate a greater benefit of antidepressants in childhood than adolescence. The median effective dosage of antidepressants administered to children ages 2 15 in the United States was approximately 70% higher in adolescence than childhood.

It is important to note, however, that effective doses of most antidepressants for children may be too high. A number of factors may play a role in this regard. The use of an SSRI is much more common among boys than girls. This might result from the stronger influence of testosterone on their mood when they are online pharmacy degrees uk young. For boys with mood disorders, this may occur before sexual development is complete and during the teenage puberty period, when testosterone levels increase.[8] Some boys may also have more genetic susceptibilities to depression than do girls.

A meta-analysis of studies involving the use antidepressants in children and adolescents Atorva 4mg $301.15 – $1.12 Per pill suggested that the mean dose of an SSRI can vary from 2.5 to 3.5 times the intended dose in this age group.[9] Given variability, children and adolescents should be prescribed the lowest effective dose of drug that is appropriate for their medical condition.

In conclusion, children ages 2 to 15 who have depressive symptoms should be monitored closely to ensure that their depression is not worsening, and should receive appropriate treatment. In particular, children with depression that is not refractory to other treatment might benefit from antidepressant medication. Also, children and adolescents should not be given more than 100 mg/day of a tricyclic antidepressant as recommended by the Food and Drug Administration to treat major depressive disorder.

The findings of this study are subject to several limitations. Because we included only antidepressants that are currently available on the market, not all patients were treated successfully atorvastatin generic cost with each of the treatments. Moreover, patients who started the medications early in puberty were more likely to continue treatment in adolescence. However, a recent prospective study did not find a clear dose-response relationship.

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